100 HLA-identical Sibling Transplants

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Graft-Versus-Host Disease in HLA-Identical Sibling Transplants Cytokine Gene Polymorphisms Associating With Severe Acute

http://bloodjournal.hematologylibrary.org/content/92/10/3943.full.html Updated information and services can be found at: (1844 articles) Transplantation • Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found on...

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Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants.

It is now well known that the initial phase of graft-versus-host disease (GVHD) involves cytokine release during preconditioning of the recipient of an allogeneic bone marrow transplant (BMT). Tumor necrosis factor (TNF), in particular, has been implicated in pathological damage and is released pretransplant due to irradiation and cytotoxic preconditioning regimens. Interleukin-10 (IL-10), a na...

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Should HLA-identical sibling bone marrow transplants for leukemia be restricted to large centers?

There is substantial evidence that the volume of medical procedures in a hospital has an inverse relationship with mortality. We analyzed data for 1313 recipients of HLA-identical sibling bone marrow transplants for early leukemia (acute leukemia in first remission or chronic myelogenous leukemia in first chronic phase) to determine whether transplant outcome differed in small and large centers...

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HLA-identical sibling stem-cell transplantation in first-remission AML.

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Evidence that CD31, CD49b, and CD62L are immunodominant minor histocompatibility antigens in HLA identical sibling bone marrow transplants.

Despite complete matching of siblings for the HLA loci, after bone marrow transplantation (BMT), approximately 20% develop graft-versus-host disease (GVHD). This is presumably due to incompatibility of minor histocompatibility antigens (mHa). We investigated the polymorphisms of 14 adhesion molecules (CD2, CD28, CD31, CD34, CD36, CD42, CD44, CD48, CD49b, CD54, CD62L, CD86, CD102, and CD106) in ...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1979

ISSN: 0003-4932

DOI: 10.1097/00000658-197902000-00013